LYOPHILIZERS NLG series are designed for carrying out effective drying of antibiotics, fabrics, proteins under vacuum and low temperature, which supports maximum safety of a product. These machines can be used in pharmaceutical and microbiological industry.
Execution of freeze dryers is based on use of the tested technology, high-quality materials and the accessories applied in pharmaceutical industry. The high level of production and quality control provides compliance of lyophilizers to GMP requirements.
Working principle
The principle of operation of freeze dryers consists in moisture evaporation from frozen product, passing a liquid phase, and its sedimentation in a condenser Lyophilizers consist of the working chamber with shelves which can be cooled and heated up, a condenser, refrigerating and vacuum systems. The installation composition also includes monitoring equipment and control system.
Process control of drying is made by operator using a programmable logic controller and an engineering panel or from the personal computer.
Taken to the consideration high cost of the product, the great value is given to safety of a product. Therefore many components of all systems are duplicated.
- Contacting parts are made of stainless steel AISI 316L.
- Roughness of internal surfaces of the working camera 0,4 µ, mirror polished.
- Special design of shelves provides coherence of temperatures.
- The option of a hydraulic sealing of bottles is provided.
- PLC control system.
- Monitoring of operation of installation from the personal computer using the special software on the basis of Windows®.
- Printout of process data in graphic and text representation.
- Installation can be optionally equipped with cleaning system on a place (CIP) and sterilization system on place (SIP).
Laboratory |
For industrial production |
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NLG |
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Model NLG |
0.4 | 1 |
3 |
5.5 | 7.7 | 10 | 15 | 20 | 24 | 30 | 40 | |||
Shelves area, м² |
0.41 | 1.08 |
2.96 |
5.54 | 7.75 | 10.33 | 14.76 | 20.63 | 24.38 | 29.7 | 40.5 | |||
Loading batch, vials pcs. |
Ø16 | 1840 | 4500 |
13300 |
24800 | 34800 | 46400 | 66400 | 92800 | 109700 | 133600 | 182200 | ||
Ø22 | 920 | 2300 |
6800 |
12700 | 17800 | 23700 | 33900 | 47400 | 56000 | 68300 | 93000 | |||
Ø30 | 510 | 1300 |
3700 |
6900 | 9600 | 12900 | 18400 | 25800 | 30500 | 37100 | 50600 | |||
Loading in trays, l |
8 | 20 |
60 |
110 | 155 | 210 | 290 | 410 | 480 | 590 | 800 | |||
Main parameters |
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Shelves |
Width, mm |
300 | 450 |
610 |
915 | 915 | 1215 | 1215 | 1250 | 1250 | 1500 | 1500 | ||
Depth, mm |
450 | 600 |
810 |
1210 | 1210 | 1215 | 1215 | 1500 | 1500 | 1800 | 1800 | |||
Model NLG |
0.4 | 1 |
3 |
5.5 | 7.7 | 10 | 15 | 20 | 24 | 30 | 40 | |||
Q-ty of shelves, pcs |
3+1 | 4+1 |
6+1 |
5+1 | 7+1 | 7+1 | 10+1 | 11+1 | 13+1 | 11+1 | 15+1 | |||
Distance between shelves, mm |
80…120 |
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Shelves temperature, ºС |
up to -45 |
-55…+80(with sterilization -55…+130) |
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Condenser tem-perature, ºС, ºС |
up to -55 |
up to -75 |
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Ice capacity, kg |
7 | 20 |
55 |
100 | 140 | 180 | 260 | 370 | 440 | 530 | 700 | |||
Vacuum, Pa |
up to 1.5 |
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Power, kW |
3.5 | 10 |
23 |
32 | 40 | 58 | 84 | 105 | 125 | 145 | 170 | |||
Defrosting water consumption l/min |
air defrosting |
5 | 8 | 11 | 14 | 20 | 27 | 30 | 33 | 36 | 42 | |||
Compressed air, MPa |
0.4~0.6 |
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Overall dimensions, mm |
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Width |
850 | 1400 |
1500 |
2200 | 2200 | 2200 | 2200 | 2300 | 2300 | 2400 | 2400 | |||
Depth |
1000 | 2400 |
3600 |
5300 | 5400 | 6300 | 6400 | 7300 | 8000 | 9000 | 9200 | |||
Height |
2200 | 2500 | 2700 |
2900 | 3100 | 3200 | 3400 | 3800 | 4000 | 4000 | 4500 | |||
NLG CIP, SIP |
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Pure steam consumption, kg/h |
- | 60 |
100 |
130 | 150 | 200 | 230 | 280 | 320 | 380 | 450 | |||
Pure water consumption, (WFI wa-ter), l/min |
? | 60 | 90 |
120 | 150 | 160 | 200 | 230 | 260 | 280 | 300 | |||
Overall dimen-sions, mm |
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Width |
1200 |
1500 |
2300 | 2300 | 2300 | 2300 | 2300 | 2300 | 2400 | 2400 | ||||
Depth |
? | 2200 |
3800 |
5500 | 5600 | 6400 | 6500 | 7400 | 8200 | 9200 | 9400 | |||
Height |
? | 2300 |
2700 |
2900 | 3100 | 3200 | 3400 | 3800 | 4000 | 4000 | 4500 | |||
All data just for reference. Shelves temperature is mentioned without product |
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